A new study has unveiled how psychedelics achieve their perception-altering effects in the human brain. The research used a powerful combination of brain analysis techniques to provide the clearest picture yet of how the short-acting, but powerful psychedelic DMT (dimethyltryptamine) affects brain activity.
DMT has a storied history. Used for thousands of years in rituals and other ceremonies across Central and South America, it is the key active component of the potent psychedelic brew ayahuasca.
More recently, the compound was synthetically created by German–Canadian chemist Richard Manske in 1931.
The DMT experience makes it particularly promising as a therapeutic psychedelic.
The University of New Mexico’s Professor Rick Strassman, an expert in the compound, describes it as inducing effects like “visions, voices, a seeming separation of consciousness from the body, extreme emotional states and contact with seemingly discarnate intelligences.”
But the compound does so over relatively short periods of time as compared to other classic psychedelics such as psilocybin. That makes it much more flexible as a tool for psychedelic-assisted psychotherapy.
But no previous study has exploited this short duration to study the effects of DMT on the human brain in high detail before, during and after a DMT trip.
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