10/24/2022
People who reported experiencing side effects to the Pfizer/BioNTech and Moderna Covid-19 vaccines such as fever, chills or muscle pain tended to have a greater antibody response following vaccination, according to new research.
Having such symptoms after vaccination is associated with greater antibody responses compared with having only pain or rash at the injection site or no symptoms at all, suggests the paper published Friday in the journal JAMA Network Open.
“In conclusion, these findings support reframing postvaccination symptoms as signals of vaccine effectiveness and reinforce guidelines for vaccine boosters in older adults,” the researchers – from Columbia University in New York, University of Vermont and Boston University – wrote in their paper.
The researchers found that after either vaccine dose, 446 or 48% of participants reported systemic symptoms while 12% reported only local symptoms and 40% reported no symptoms at all.
Meanwhile, antibody reactivity was observed in 444 or 99% of participants with systemic symptoms, 99% of those with only local symptoms and 98% of those with no symptoms.
Full Link ( CDC )
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